Amplification in Dedifferentiating Cells - The first results on DNA amplification during dedifferentiation are derived from knowledge obtained from wound healing experiments mainly carried out to gain in sight into the problem of Agrobacterium tumefaciens induced tumorigenesis.

These studies are related in particular to the so called conditioning phase, i.e., a period between wound and infection with the bacterium.

A sharp increase in DNA after wounding has been reported which was not associated with mitosis.