List
of
Products
(Recombinant
Proteins)
Generated
Using
Recombinant
DNA
Technology
| Product (protein) | Gene expressed in (host) | Application |
| Currently in Therapeutic Use | ||
| Human growth horomone (HGH) | Mouse mammary tumour cell line | Dwarfism |
| Tissue plasminogen avtivator (TPA) | Chenese hamster ovary (CHO)cell line | Thrombolysis |
| Erythropoietin * | (CHO)cell line | Anaemia |
| Blood clotting factor VIII* | (CHO)cell line | HaemophiliaF |
In Advanced Stages of Development |
||
| Antithrombin VIII | (CHO)cell line | Anticoagulant |
| Blood factor VIII | BHK-21 cell line | Haemophilia |
| Blood factor IX | CHO cell line | Haemophilia-B |
Interleukin-2 (11-2) |
- | Cancer therapy |
| Human recombinant antibodies | CHO cell line and Mouse myeloma lines | Infections, various cancers |
Hepatitis-B surface antigen (HBSAg) |
CHO cell line and C-127 cell line | As vaccine Hepatitis-B |
Interferons (IFN) |
- | Tumours |
Plasminogen activator (including chimeric and modified) |
CHO cell line and Spodoptera frugiperda |
Thrombolysis |
CD4 Protein |
Mammalian cell line | AIDS vaccine |
gp 160 protein |
Mammalian cell line | AIDS vaccine |
p24 protein |
Mammalian cell line | AIDS vaccine |
Interleukin-l receptor antagonist |
Mammalian cell line | Severe sepsis |
| Atrial natriuretic | Mammalian cell line | Kidney failure |
| Ciliary neurotropic factor | Mammalian cell line | Amyotrophic sclerosis |
DNase |
Mammalian cell line | Cystic fibrosis |