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Organ Culture - In vitro culture and growth of organs or parts thereof in which their various tissue components, e.g., parenchyma and stroma, are preserved both in terms of their structure and function so that the cultured organs resemble closely the concerned organs in vivo is called organ culture.

In such cultures, new growth is in the form of differentiated structures, e.g., glandular structures in case of glands, small bronchi in case of lung tissues, etc., in tissues lined with one or the other type of epithelium, the epithelium differentiates in a pattern similar to that in the concerned organs in vivo.

The cultured organs retain their physiological features, e.g., hormone dependent organs remain hormone dependent, and endocrine organ go on secreting the specific hormones.

In addition, the morphogenesis in cultured foetal tissues is more or less comparable to that in vivo. In case of organ cultures, outgrowth of isolated cells from the periphery of explants is minimised by manipulating the culture conditions.