Roller Bottle - This vessel permits a limited scale up as it is rocked or preferably, rolled so that its entire internal surface is available for anchorage. Several modifications of roller bottle further enhance the available surface, e.g.,

(i) Spira-Cel (spiral polystyrene cartridge),

(ii) glass tube (roller bottle packed with a parallel cluster of small glass tubes separated by silicone spacer rings), and

(iii) extended surface area roller bottle (the bottle surface is corrugated enhancing the surface by a factor of two), etc.