DNA Vaccines -

Recently, vaccines based on DNA are being developed, and the results obtained with influenza virus (advanced stages of testing) are quite exciting; these are regarded as the third revolution in vaccines. The strategy of DNA vaccines is as follows. The gene encoding the relevant immunogenic protein is isolated, cloned and then integrated into a suitable expression vector.

This preparation is introduced into the individual to be immunised. The gene is ultimately expressed in the vaccinated individual and the immunogenic protein is expressed in sufficient quantities to invoke both humoral and cell mediated immunities.