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Examples of Autoantibodies Used as Disease Specific Marker for Diagnosis-

Antibody Antigen specific to Associated clinical condition
Anti-ds DNA* B form of DNA Systemic lupus erythematosus
Anti-Jo-1 Histidyl-tRNA synthetase Polymyositis
Anti-RNA polymerase I Subunits of RNA polymerase I Scleroderma
Anti-centromere Centromeric proteins CREST (a subset of scleroderma)
Anti-acetylcholine receptor Acetylcholine receptor Myasthenia gravis
Anti-mitochondria Pyruvate dehydrogenase complex Primary biliary cirrhosis

 

 

 

 
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