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Embryo Therapy - This will involve the following steps, which have been tried in case of mouse or rabbit only:

(i) in vitro fertilization of the egg,
(ii) insertion of normal gene into embryo at post zygotic level, either with viruses or directly by microinjection,
(iii) integration of inserted gene in host DNA, where it mayor may not function.

The inserted genes have been found to be inactive generally, but in few animals, where genes have been switched on in a tissue specific way, their activity is at a very low level. However, it is not yet possible that the therapeutic newly inserted genes function under normal control in the animal, in time, space and quantity.