Enzyme Engineering - Improvement in the activity and usefulness of an existing enzyme or creation of a new enzyme activity by making suitable changes in its amino acid sequence is called enzyme engineering. When this approach is used to modify the properties of any protein, whether enzyme or nonenzyme, it is termed as protein engineering.

Since enzymes are proteins, enzyme engineering is a part of the larger activity of protein engineering. Enzyme engineering utilizes recombinant DNA technology to introduce the desired changes in the amino acid sequences of enzymes.