Immobilization of Enzymes by Membrane Confinement - Enzyme molecules, usually in an aqueous solution, may be confined within a semipermeable membrane which, ideally, allows a free movement in either direction to the substrates and products but does not permit the enzyme molecules to escape. A number of strategies are employed for this purpose; the simplest strategy is as follows.

The reaction vessel is partitioned into two chambers by a semipermeable membrane; one chamber contains the enzyme while the other has the substrate and the product. Each immobilization strategy has some strong.