These reactors are,
(i) easy to establish,
(ii) permit the use of more than one enzyme to catalyze a chain of reactions,
(iii) allow easy replacement of enzymes, and
(iv) are useful in producing small scale (g to kg) quantities.
The chief limitations of these systems are:
(i) regular replacement of membranes adds to cost and,
(ii) the need for substrate diffusion through the membrane often limits its applications



