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Membrane Reactors
A membrane reactor uses a membrane, e.g., dialysis membrane, to contain the enzyme in a chamber into which the substrate moves and the product moves out. Generally, membrane reactors use a hollow fiber of 200 /lm diameter with 50 /lm thick membranes.

Each reactor contains hundreds of such fibers into which the enzyme is retained; usually these reactors use soluble enzymes. The substrate is kept in the main chamber of the reactor. These reactors can also be used in a continuous mode and the substrate flow rate is adjusted to achieve the desired level of reaction.

These reactors are,

(i) easy to establish,

(ii) permit the use of more than one enzyme to catalyze a chain of reactions,

(iii) allow easy replacement of enzymes, and

(iv) are useful in producing small scale (g to kg) quantities.

The chief limitations of these systems are:

(i) regular replacement of membranes adds to cost and,

(ii) the need for substrate diffusion through the membrane often limits its applications