Therefore, initially, plant and animal enzymes were preferred over microbial enzymes mainly for considerations of safety and the fear of contamination by microorganisms, toxins, etc.
But increased demands, shortages in supplies of enzymes from plant and animal sources, and difficulties in maintaining a continued supply of these enzymes prompted a much closer and more pragmatic evaluation of the microbial enzymes.
These enzymes have found increasing applications even in such areas where enzymes of animal origin were once exclusively used, e.g., cheese production. The rennet (= aspartic proteinase) produced by Mucor miehei is now widely used for cheese production.
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