Selectable
Marker
Genes
in
Vectors
Used
for
Gene
Transfer
| Selectable marker gene | Substrate used for selection |
| I. Antibiotics | |
1. Neomycin phosphotransferase (npt II) |
G418, kanamycin, neomycin |
2. Hygromycin phosphotransferase (hpt) |
Hygromycin B |
| 3. Dihydrofoate reductase (dhfr) | Methotrexate trimethoprim |
4. Gene ble (enzyme not known) |
Bleomycin |
5. Gentamycin acetyltransferase |
Gentamycin |
| 6. Streptomycin phosphotransferase | Streptomycin |
II. Herbicides |
|
7. Mutant form of acetolactate synthase (als) |
Chlorosulfuron imidazolinones |
| 8. Bromoxynil nitrilase | Bromoxynil |
| 9. Phosphinothricin acetyl transferase (bar) | L - phosphinothricin (PPT; also known as bialaphos) |
| 10. S. enolpyruvylshikimate -3 –phosphate (EPSP) synthase (aro A) | Glyphosate (Roundup) |