Conformational Flexibility of DNA Molecule, Nucleotide Sequence, Double Helix, B Form DNA, Aqueous Protoplasm

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	Conformational Flexibility of DNA Molecule - DNA is not a fixed and static invariant molecule. On the contrary, DNA molecules exhibit a considerable amount of conformational flexibility. These alternative forms of DNA have received increasing attention in recent years as it has been shown that the nucleotide sequence is one of the factors that influence the form taken by a segment of the double helix.
The structure for DNA in a fibre is produced at a very high relative humidity (92%). This is called the B-form of DNA. The vast majority of the DNA molecules present in the aqueous protoplasm of living cells almost certainly exist in the B-form. The structure of DNA molecules change as a function of their environment. The exact conformation of a given DNA molecule or segment of DNA molecules will depend on the nature of the molecule with which it is interacting and amount of water content.