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Historical Genome Sequencing- The idea of genome sequencing was discussed in the scientific community during 1984 onwards. In 1986, a proposal was prepared for sequencing of the human genome. The human genome project officially began on Oct. 1, 1990. The first genome to be sequenced was that of Haemophilus influenzae in 1995.

The E. coli genome was soon to be completely sequenced in 1997.

Yeast (Saccharomyces cerevisiae) and worm (Caenorhabditis elegans) genomes were the first eukaryotic genomes to be sequenced in 1999. One year later, in 2000, genomes of Drosophila melanogaster and Arabidopsis thaliana were sequenced.

On June 26, 2001, the rough draft of human genome was announced. This draft was prepared separately by the public-funded Human Genome Sequencing Consortium and the private company Celera Genomics established by Craig Venter. However, the draft sequence was announced jointly after intervention by the U.S. President.