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Nucleotide Sequence Databases- The major nucleotide sequence databases are Gene Bank held by NCBI, USA, DNA Databank of Japan (DDBJ), and the Nucleotide Sequence Database maintained by EMBL. In addition, several other nucleotide sequence databases have been created.

1. Gene Bank. This is the main nucleotide sequence database held by NCBI, USA. This database contains nucleotide sequences of genomic DNA.

2. dbEST. This database contains EST entries from GeneBank, EMBL and DDBJ databases. This database is likely to have sequencing errors, Contamination by heterologous sequences and the presence of transcribed repetitive elements. The database is held by NCBI, USA.

3. E. coli. This database is held by NCBI, USA. It has nucleotide sequence of E. coli genome.

4. Mito. This database contains sequences of mitochondrial genomes and is held at NCBI, USA.

5. EMBL. This is a comprehensive nucleotide (DNA and RNA) sequence database held at EMBL and compiled from various sources. It is collaboration between the GeneBank database at NCBI, USA and the DDBJ at GenomeNet, Japan. EMBL communicates with GeneBank and DDBJ on daily basis and updates its contents.

6. Kabat. This database is held at NCBI, USA. It has nucleotide sequences that are of interest from immunological point of view.

7. IMGT Database. (The International Immunogenetics Database): This database has nucleotide sequence of immunologically important genes, e.g., T-cell receptors, B-cell receptors, etc.

 

  

 
   
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