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Analytical Synthetic Breeding in Potato -  Another approach described as 'analytical synthetic breeding scheme’ has been described by Wenzel et al. (1979).

This takes advantage of protoplast fusion and plant regenera­tion to bring together different genotypes into a completely heterozygous tetraploid potato. In this approach; dihaploids are used again for the production of monohaploids, before the tetraploid is resynthesized. The breeder can evaluate and select the genomes present in monoploids.

The selected monoploids are then used for resynthesis of tetraploid through protoplast fusion and regeneration as follows: (monoploid} + monoploid4) + (monoploid3 + monoploid4). The selection of best somatic hybrids may be feasible on the basis of their growth rate in cell cultures.

The above scheme of analytical synthesis can be easily used in potato, because once the resynthesized tetraploids are regenerated, they can be multiplied via tubers for commercial cultivation.

In other autotetraploid crops like alfalfa (Medicago sativa) or orchardgrass (Dactylis glomerata), where reproduction is by seed, the above scheme will not be successful. However, the analytical breeding described earlier can be used. In alfalfa, when 2n gametes function, the two schemes suggested by Mendiburu and Peloquin (1977) for potato can also be used.