Transfer of Promising Natural Moftis - Gene for Vitreoscilla haemoglobin (VHb), which helps in cell growth and product synthesis under limited oxygen supply, has been transferred to E.coli, Streptomyces lividans and S. coelicolor. (Vitreoscilla is a gram negative aerobic bacterium).

Under limited supply of oxygen, the expression of VHb gene in E. coli and Streptomyces allowed much more rapid synthesis of total cell protein. A motif in VHb, perhaps increases efficiency of net ATP synthesis, facilitates oxygen transfer to respiratory centre, and modifies some aspect of cellular redox chemistry.

This strategy may be used for production under stress conditions. Genes for resistance against other stresses may also be used in future for production of specific proteins under these other stress conditions (e.g. abnormal temperature and pH).