Industrial
Applications
of
Molecular
Biotechnology
- Recombinant
DNA
technology
does
not
just
offer
novel
methods
for
the
generation
of
proteins,
it
also
provides
new
ways
of
making
low
molecular
weight
compounds.
A
good
example
is
the
microbial
synthesis
of
the
blue
dye
indigo
and
the
black
pigment
melanin.
Neither
of
these
compounds
is
normally
produced
by
microbes.
The
cloning
of
a
single
gene
from
Pseudomonas
putida,
that
encodes
naphthalene
dioxygenase,
results
in
the
generation
of
an
E.
coli
strain
able
to
synthesize
indigo
in
a
medium
containing
tryptophan.
Just
as
novel
proteins
can
be
produced
by
recombinant
DNA
techniques
so
too
can
novel
small
molecules.



