Advantages and Disadvantages of Finite and Continous Cell Lines -

Features	Finite	Continuous
1. Ploidy	Diploid Euploid	Heteroploid Aneuploid
2. Transformation	Normal	Transformed
3. Tomourigenicity	Non-tumourigenic	No Tumourigenic
4. Anchorage Dependence	Yes	No
5. Contact Inhibition	Yes	No
6. Density Limitation of Growth	Yes	No
7. Mode of Growth	Monolayer	Monolayer of Suspension.
8. Maintenance	Cyclic	Steady State Possible.
9. Serum Requirement	High	Low
10. Cloning Efficiency	Low	High
11. Markers	May be tissue specific	Chromosomal, enzymic
12.Special Functions	May be retained	Often lost
13. Growth Rate	Slow	Rapid
14. Yield	Low	High
15. Control Features.	Generation Number in vivo markers	Strain Characteristics