Properties of Good Host - A good host should have the following features:
(1) be easy to transform,
(2) support the replication of recombinant DNA,
(3) be free from elements that interfere with replication of recombinant DNA,
(4) lack active restriction enzymes, e.g., E. coli K12 substrain HB101,
(5) should not have methylases since these enzymes would methylate the replicated recombinant DNA. which, as a result, would become resistant to useful restriction enzymes, and