Back to Home
Home >>Regulation of Gene Expression - in Prokaryotes >> Functions of Lac Operon
Back to Home

Functions of Lac Operon - In the presence of lactose, the lactose binds to the repressor and prevents it from binding to the promoter by inducing structural changes in the repressor. Then the RNA polymerase binds to the promoter and starts the transcription of the structural gene.

The structural gene is expressed as a single transcript. But different ribosomes bind to RNA transcript each at the starting of each cistron. Thus it makes the protein. These proteins then break down the lactose into glucose units. This gene expression continues as long as lactose is present in the media.

Once the lactose gets depleted in the media, the repressor binds to the operator gene and stops the transcription of the structural gene. The basic reason for this on and off of the gene is to ensure that the bacteria makes only the protein responsible OR required at the particular time.

Thus avoiding the wastage of resources and energy on preparing proteins that are not required at that moment. As long as the lactose is absent in the media the repressor binds to the operator gene. Thus the transcription of the structural gene does not take place.