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Sliding
OR
Tracking
in
Transcription -
Sliding is also referred to as tracking. This mechanism imagines that a protein recognizes a specific site on DNA and then moves along the DNA to another specific sequence where perhaps by interacting with another protein, it initiates transcription.
Regulatory proteins are not known to act by sliding but this process is important for many other precise DNA transactions. Type I restriction enzymes bind their unique recognition sequences and cleave the DNA at sites that can be thousands of base pairs away. This is possible only through tracking.
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