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Plant Derived Vaccines -

Conventional vaccines consist of attenuated or inactivated pathogens. In case of many pathogens, the gene encoding a critical antigen has been isolated and expressed in bacteria/animals, and the recombinant protein so produced is used as a vaccine; such vaccines are called recombinant vaccines.

Recombinant vaccines are produced through bacterial fermation or in animal cell cultures, which often makes their cost prohibitively high. In addition, storage and transport of vaccines, especially in developing countries, presents many problems, e.g., cold storage.

Therefore, plants are being developed as an alternative vaccine production and delivery systems. There are two basic objectives of such efforts:
(1) development of edible vaccines, and
(2) production of recombinant antigenic proteins to be used as vaccines