| Active principle of herbicide |
Inhibited pathway |
Target product |
Use |
Basis of resistance |
| I.Amino acid biosynthesis inhibitors |
| 1.Glyphosate (Roundup) |
Aromatic amino acid biosynthsis |
EPSPS |
Broad spectrum |
Overexpression of EPSPS gene; bacterial aroA gene |
| 2.Sulphonylurea and Imidazolinones |
Branched chain amino acids |
ALS |
Selected crops |
Mutant ALS gene |
| 3.Phosphinothricin (Basta) |
Glutamine biosynthesis |
GS |
Broad spectrum |
Gene amplification, bar gene: detoxification |
| II. Photosynthesis inhibitors |
| 4. Atrazine (Lasso) |
Photosystem II |
QB (32 kDa protein) |
Selected crops |
Mutant PsbA gene, GST gent; detoxification |
| 5. Bromoxynil (Buctril) |
Photosynthesis |
-- |
Selected crops |
bxn gene; detoxification |